{"Abbreviation":"BPA","Aliases":["4,4'-Isopropylidenediphenol","2,2-Bis(p-hydroxyphenyl)propane","Diphenylolpropane","4,4'-Bisphenol A","Diano","Bisphenol-A","Biphenol A","Parabis A","4,4'-(propane-2,2-diyl)diphenol","DIAN"],"Biological Half-Life":"... Following a single oral or intravenous (iv) dose of 100 ug/kg (ring-(14)C(U)) radiolabeled bisphenol A ((14)C-BPA) to male and female cynomolgus monkeys ... the terminal elimination half-life was larger post-iv dose (t(1/2iv) = 13.5 to 14.7 hr) than post-oral dose (t(1/2oral) = 9.63 to 9.80 hr). After iv dose, the fast-phase half-life (t(1/2f)) of total radioactivity was 0.61 to 0.67 hr. The t(1/2f) of unchanged (14)C-BPA for females (0.39 hr) was smaller than that for males (0.57 hr).","Boiling Point":"428 °","CAS":"80-05-7","ChEBI":"CHEBI:33216","ChEMBL":"CHEMBL418971","ChemicalClasses":["phenol"],"Chirality":"achiral","Classes":null,"Color/Form":"Crystallizes as prisms from dil acetic acid and as needles from water","Decomposition":"Hazardous decomposition products formed under fire conditions - Carbon oxides.","Density":"1.195 at 77 °F (USCG, 1999) - Denser than water; will sink g/cm\u003csup\u003e3\u003c/sup\u003e","Dosing Info":[],"DrugClasses":[],"EINECS":"201-245-8","European Community (EC) Number":"201-245-8","Flash Point":"175 °F (NTP, 1992)","HMDB ID":"HMDB0032133","HeavyAtomCount":17,"IUPACName":"4-[2-(4-hydroxyphenyl)propan-2-yl]phenol","InChI":"InChI=1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3","InChIKey":"IISBACLAFKSPIT-UHFFFAOYSA-N","MeSH Pharmacological Classification":"Toxic air-borne matter related to work performed They are usually produced by the specific nature of the occupation. (See all compounds classified as Air Pollutants, Occupational.)","Melting Point":"307 to 313 °F (NTP, 1992)","MolecularFormula":"C\u003csub\u003e15\u003c/sub\u003eH\u003csub\u003e16\u003c/sub\u003eO\u003csub\u003e2\u003c/sub\u003e","MolecularWeight":"228.29 g/mol","Odor":"Mild phenolic odor","Physical Description":"4,4'-isopropylidenediphenol appears as white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)","PrevSalts":[],"PubChemId":6623,"Record Description":["Bisphenol A (BPA) can cause developmental toxicity according to The National Toxicology Program's Center for the Evaluation of Risks to Human Reproduction. It can cause female reproductive toxicity according to an independent committee of scientific and health experts.","4,4'-isopropylidenediphenol appears as white to light brown flakes or powder. Has a weak medicine odor. Sinks in water. (USCG, 1999)","Bisphenol A is a bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. It has a role as a xenoestrogen, an environmental contaminant, a xenobiotic and an endocrine disruptor.","Bisphenol A is a diphenylmethane derivative with two hydroxyphenyl groups. Bisphenol A (BPA) is a colorless solid that is used in the synthesis of commercial plastics, including polycarbonates and epoxy resins, which are incorporated into a wide variety of consumer goods. Ingested BPA may exhibit estrogenic effects. Exposure to BPA may increase the risk of certain cancers.","Bisphenol A, commonly abbreviated as BPA, is an organic compound with two phenol functional groups. It is a difunctional building block of several important plastics and plastic additives. With an annual production of 2-3 million metric tonnes, it is an important monomer in the production of polycarbonate. It is a potential food contaminant arising from its use in reusable polycarbonate food containers such as water carboys, baby bottles and kitchen utensils.\n\n\n\nSuspected of being hazardous to humans since the 1930s, concerns about the use of bisphenol A in consumer products were regularly reported in the news media in 2008 after several governments issued reports questioning its safety, and some retailers removed baby bottles and other children's products made from it from their shelves.","See also: Anoxomer (monomer of); Polycarbonate (annotation moved to).","Bisphenol A (BPA) can cause developmental toxicity according to The National Toxicology Program's Center for the Evaluation of Risks to Human Reproduction. It can cause female reproductive toxicity according to an independent committee of scientific and health experts.","Bisphenol A is a bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. It has a role as a xenoestrogen, an environmental contaminant, a xenobiotic and an endocrine disruptor."],"References":[{"Name":"Wikipedia","Urls":[{"Link":"https://en.wikipedia.org/wiki/Bisphenol_A","Name":"Bisphenol A","Sub":false}]},{"Name":"Wikidata","Urls":[{"Link":"https://www.wikidata.org/wiki/Q271980","Name":"Bisphenol A","Sub":false}]},{"Name":"DrugBank","Urls":[{"Link":"https://go.drugbank.com/drugs/DB06973","Name":"Bisphenol A","Sub":false}]},{"Name":"PubChem","Urls":[{"Link":"https://pubchem.ncbi.nlm.nih.gov/compound/6623","Name":"Bisphenol A","Sub":false}]},{"Name":"ChEMBL","Urls":[{"Link":"https://www.ebi.ac.uk/chembl/explore/compound/CHEMBL418971","Name":"Bisphenol A","Sub":false}]},{"Name":"ChEBI","Urls":[{"Link":"https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:33216","Name":"Bisphenol A","Sub":false}]},{"Name":"Common Chemistry","Urls":[{"Link":"https://commonchemistry.cas.org/detail?cas_rn=80-05-7","Name":"Bisphenol A","Sub":false}]},{"Name":"HMDB","Urls":[{"Link":"https://hmdb.ca/metabolites/HMDB0032133","Name":"Bisphenol A","Sub":false}]},{"Name":"KEGG","Urls":[{"Link":"https://www.kegg.jp/entry/C13624","Name":"Bisphenol A","Sub":false}]},{"Name":"UNII","Urls":[{"Link":"https://gsrs.ncats.nih.gov/ginas/app/ui/substances/MLT3645I99","Name":"Bisphenol A","Sub":false}]},{"Name":"EPA DSSTox","Urls":[{"Link":"https://comptox.epa.gov/dashboard/chemical/details/DTXSID7020182","Name":"Bisphenol A","Sub":false}]}],"SMILES":"CC(C)(C1=CC=C(C=C1)O)C2=CC=C(C=C2)O","Solubility":"less than 1 mg/mL at 70.7 °F (NTP, 1992)","Stability/Shelf Life":"Stable under recommended storage conditions.","StoreUNII":["MLT3645I99"],"StructureBase64":"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A","UNII":"MLT3645I99","Wikidata":"Q271980","Wikipedia":"Bisphenol_A","XLogP":3.3}